HYDRO-1 is a technology for the treatment and reuse of municipal wastewater. The system fulfils Class A requirements for reclaimed water in terms of TSS, BOD5, and Turbidity, according to the EU Regulation 2020/741. Composed by anaerobic treatment followed by nature-based solutions (NBS) with constructed wetland (CW), HYDRO-1 in combination with a disinfection unit permits to reuse and recover of water and nutrients with minimum operational and maintenance cost in comparison to conventional technologies (lower sludge production, and manpower).